Les publications

Page en cours de mise à jour... Retrouvez ici les publications des équipes de recherche du CGO

Réseaux Appels à projets Actualités
384 publications
Année de publication :
Réseaux :

Increased antitumor efficacy of PD-1-deficient melanoma-specific human lymphocytes

Background: Genome editing offers unique perspectives for optimizing the functional properties of T cells for adoptive cell transfer purposes. So far, PDCD1 editing has been successfully tested mainly in chimeric antigen receptor T (CAR-T) cells and human primary T cells.

  • Ref: DOI: 10.1136/jitc-2019-000311
  • Année de publication : 2020
  • Auteurs : Marotte L, Simon S, Vignard V, Dupre E, Gantier M, Cruard J, Alberge JB, Hussong M, Deleine C, Heslan JM, Shaffer J, Beauvais T, Gaschet J, Scotet E, Fradin D, Jarry A, Nguyen T, Labarriere N. J Immunother
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

New insights on the role of ROS in the mechanisms of sonoporation-mediated gene delivery

Reactive oxygen species (ROS) are hypothesized to play a role in the sonoporation mechanisms. Nevertheless, the acoustical phenomenon behind the ROS production as well as the exact mechanisms of ROS action involved in the increased cell membrane permeability are still not fully understood

  • Ref: DOI: 10.1016/j.ultsonch.2020.104998
  • Année de publication : 2020
  • Auteurs : Escoffre JM, Campomanes P, Tarek M, Bouakaz A.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
Lire la publication

Picolinate-appended tacn complexes for bimodal imaging: Radiolabeling, relaxivity, photophysical and electrochemical studies

Based on our previous works involving two ,4,7-triazacyclononane (tacn)-based ligands Hno2py1pa (1-Picolinic acid-4,7-bis(pyridin-2-ylmethyl)-,4,7-triazacyclononane) and Hno1pa (1-Picolinic acid-,4,7-triazacyclononane)…

  • Ref: DOI: 10.1016/j.jinorgbio.2019.110978
  • Année de publication : 2020
  • Auteurs : Guillou A, Galland M, Roux A, Váradi B, Gogolák RA, Le Saëc P, Faivre-Chauvet A, Beyler M, Bucher C, Tircsó G, Patinec V, Maury O, Tripier R. J
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
Lire la publication

Imaging of Monoclonal Gammapathy of Undetermined Significance and Smoldering Multiple Myeloma

Multiple myeloma (MM) is always preceded by an initial monoclonal gammopathy of undetermined significance (MGUS) that then develops into asymptomatic or smoldering multiple myeloma (SMM), which constitutes an intermediate clinical stage between MGUS and MM.

  • Ref: DOI: 10.3390/cancers12020486
  • Année de publication : 2020
  • Auteurs : Jamet B, Bailly C, Carlier T, Touzeau C, Michaud AV, Bourgeois M, Moreau P, Bodet-Milin C, Kraeber-Bodere F.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
Lire la publication