Les publications

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407 publications
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Leukemic evolution of polycythemia vera and essential thrombocythemia: genomic profiles predict time to transformation.

Among myeloproliferative neoplasms, polycythemia vera (PV) and essential thrombocythemia (ET) are the 2 entities associated with the most chronic disease course. Leukemic evolution occurs rarely but has a grim prognosis.

  • Ref: Blood Adv. 2020 Oct 13;4(19):4887-4897.
  • Année de publication : 2020
  • Auteurs : Luque Paz D, Jouanneau-Courville R, Riou J, Ianotto JC, Boyer F, Chauveau A, Renard M, Chomel JC, Cayssials E, Gallego-Hernanz MP, Pastoret C, Murati A, Courtier F, Rousselet MC, Quintin-Roué I, Cottin L, Orvain C, Thépot S, Chrétien JM, Delneste Y, Ifrah N, Blanchet O, Hunault-Berger M, Lippert E, Ugo V.
  • Réseaux : Réseaux: « Immunothérapies »
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Neurofibromin Structure, Functions and Regulation.

Neurofibromin is a large and multifunctional protein encoded by the tumor suppressor gene NF1, mutations of which cause the tumor predisposition syndrome neurofibromatosis type 1 (NF1).

  • Ref: Cells. 2020 Oct 27;9(11):E2365.
  • Année de publication : 2020
  • Auteurs : Bergoug M, Doudeau M, Godin F, Mosrin C, Vallée B, Bénédetti H.
  • Réseaux : Réseaux: « Molécules Marines, Métabolisme et Cancer »
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African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer.

Polygenic hazard score (PHS) models are associated with age at diagnosis of prostate cancer. Our model developed in Europeans (PHS46) showed reduced performance in men with African genetic ancestry.

  • Ref: Int J Cancer. 2020 Sep 15.
  • Année de publication : 2020
  • Auteurs : Karunamuni RA, Huynh-Le MP, Fan CC, Thompson W, Eeles RA, Kote-Jarai Z, Muir K; UKGPCS Collaborators, Lophatananon A, Tangen CM, Goodman PJ, Thompson IM Jr, Blot WJ, Zheng W, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Park JY, Lin HY, Bensen JT, Fontham ETH, Mohler JL, Taylor JA, Multigner L, Blanchet P, Brureau L, Romana M, Leach RJ, John EM, Fowke J, Bush WS, Aldrich M, Crawford DC, Srivastava S, Cullen JC, Petrovics G, Parent MÉ, Hu JJ, Sanderson M, Mills IG, Andreassen OA, Dale AM, Seibert TM; PRACTICAL Consortium.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Phase II Study of Pembrolizumab As First-Line, Single-Drug Therapy for Patients With Unresectable Cutaneous Squamous Cell…

Purpose: To evaluate first-line pembrolizumab monotherapy efficacy and safety in patients with unresectable cutaneous squamous cell carcinomas (CSCCs).

  • Ref: J Clin Oncol. 2020 Sep 10;38(26):3051-3061.
  • Année de publication : 2020
  • Auteurs : Maubec E, Boubaya M, Petrow P, Beylot-Barry M, Basset-Seguin N, Deschamps L, Grob JJ, Dréno B, Scheer- Senyarich I, Bloch-Queyrat C, Leccia MT, Stefan A, Saiag P, Grange F, Meyer N, de Quatrebarbes J, Dinulescu M, Legoupil D, Machet L, Dereure O, Zehou O, Montaudié H, Wierzbicka-Hainaut E, Le Corre Y, Mansard S, Guégan S, Arnault JP, Dalac S, Aubin F, Alloux C, Lopez I, Cherbal S, Tibi A, Lévy V.
  • Réseaux : Réseaux: non classé
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Management of Patients with Node-positive Prostate Cancer at Radical Prostatectomy and Pelvic Lymph Node Dissection.

Context: Optimal management of prostate cancer (PCa) patients with lymph node invasion at radical prostatectomy and pelvic lymph node dissection still remains unclear.

  • Ref: Eur Urol Oncol. 2020 Oct;3(5):565-581.
  • Année de publication : 2020
  • Auteurs : Marra G, Valerio M, Heidegger I, Tsaur I, Mathieu R, Ceci F, Ploussard G, van den Bergh RCN, Kretschmer A, Thibault C, Ost P, Tilki D, Kasivisvanathan V, Moschini M, Sanchez-Salas R, Gontero P, Karnes RJ, Montorsi F, Gandaglia G; EAU-YAU Prostate Cancer Working Party.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Overall survival among chemotherapy-naïve castration-resistant prostate cancer patients under abiraterone versus enzalutamide.

Abiraterone acetate (ABI) and enzalutamide (ENZ) are considered to be clinically relevant comparators among chemotherapy-naive patients with castration-resistant prostate cancer.

  • Ref: Am J Epidemiol. 2020 Sep 18:kwaa190.
  • Année de publication : 2020
  • Auteurs : Scailteux LM, Campillo-Gimenez B, Kerbrat S, Despas F, Mathieu R, Vincendeau S, Balusson F, Happe A, Nowak E, Oger E.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Overview of Radiolabeled Somatostatin Analogs for Cancer Imaging and Therapy.

Identified in 1973, somatostatin (SST) is a cyclic hormone peptide with a short biological half-life. Somatostatin receptors (SSTRs) are widely expressed in the whole body, with five subtypes described.

  • Ref: Molecules. 2020 Sep 2;25(17):4012.
  • Année de publication : 2020
  • Auteurs : Eychenne R, Bouvry C, Bourgeois M, Loyer P, Benoist E, Lepareur N.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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Use of radiomics in the radiation oncology setting: Where do we stand and what do we…

Radiomics is a field that has been growing rapidly for the past ten years in medical imaging and more particularly in oncology where the primary objective is to contribute to personalised and predictive medicine.

  • Ref: Cancer Radiother. 2020 Oct;24(6-7):755-761.
  • Année de publication : 2020
  • Auteurs : Schick U, Lucia F, Bourbonne V, Dissaux G, Pradier O, Jaouen V, Tixier F, Visvikis D, Hatt M.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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