Les publications

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422 publications
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Stromal cells regulate malignant B-cell spatial organization, survival, and drug response in a new 3D model…

Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as densely packed aggregates of tumor cells and their surrounding microenvironment, creating a tumor niche specific to each lymphoma subtypes.

  • Ref: BioRxiv Posted October 17, 2020.
  • Année de publication : 2020
  • Auteurs : Lamaison C, Latour S, Hélaine N, Le Morvan V, Monvoisin C, Mahouche I, Dussert C, Dessauge E, Pangault C, Seffals M, Broca-Brisson L, Alessandri K, Soubeyran P, Mourcin F, Nassoy P, Recher G, Tarte K.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
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Human Lymphoid Stromal Cells Contribute to Polarization of Follicular T Cells Into IL-4 Secreting Cells.

Fibroblastic reticular cells (FRCs) are the specialized lymphoid stromal cells initially identified as triggering T-cell recruitment and dynamic motion in secondary lymphoid organs. Interestingly, FRCs also display antigen presentation capacities and support lymphocyte survival. CXCR5+CD4+ follicular T cells are important players of B-cell maturation and antibody response.

  • Ref: Front Immunol. 2020 Oct 2;11:559866.
  • Année de publication : 2020
  • Auteurs : Misiak J, Jean R, Rodriguez S, Deleurme L, Lamy T, Tarte K, Amé-Thomas P.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
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Prognostic impact of cancer stem cell markers ABCB1, NEO1 and HIST1H2AE in colorectal cancer.

Colon cancer develops according to a defined temporal sequence of genetic and epigenetic molecular events that may primarily affect cancer stem cells.

  • Ref: Am J Transl Res. 2020 Sep 15;12(9):5797-5807.
  • Année de publication : 2020
  • Auteurs : Badic B, Durand S, El Khoury F, De La Grange P, Gentien D, Simon B, Le Jossic-Corcos C, Corcos L.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
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Three-Dimensional Culture Systems in Gastric Cancer Research.

Gastric cancer (GC), which includes cancer of the esophagus, the oesophagogastric junction, and the stomach fundus, is highly deadly with strong regional influence, Asia being the most affected.

  • Ref: Cancers (Basel). 2020 Sep 29;12(10):2800.
  • Année de publication : 2020
  • Auteurs : Alzeeb G, Metges JP, Corcos L, Le Jossic-Corcos C.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
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The emerging potential of cold atmospheric plasma in skin biology.

The maintenance of skin integrity is crucial to ensure the physiological barrier against exogenous compounds, microorganisms and dehydration but also to fulfill social and aesthetic purposes.

  • Ref: Free Radic Biol Med. 2020 Oct 8;161:290-304.
  • Année de publication : 2020
  • Auteurs : Busco G, Robert E, Chettouh-Hammas N, Pouvesle JM, Grillon C.
  • Réseaux : Réseaux: non classé
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Need for risk-adapted therapy for malignant ovarian germ cell tumors: A large multicenter analysis of germ…

Malignant ovarian germ cell tumors are rare tumors, affecting young women with a generally favorable prognosis.

  • Ref: Gynecol Oncol. 2020 Sep;158(3):666-672.
  • Année de publication : 2020
  • Auteurs : Derquin F, Floquet A, Hardy-Bessard AC, Edeline J, Lotz JP, Alexandre J, Pautier P, Angeles MA, Delanoy N, Lefeuvre-Plesse C, Cancel M, Treilleux I, Augereau P, Lavoue V, Kalbacher E, Berton Rigaud D, Selle F, Nadeau C, Gantzer J, Joly F, Guillemet C, Pomel C, Favier L, Abdeddaim C, Venat-Bouvet L, Provansal M, Fabbro M, Kaminsky MC, Lortholary A, Lecuru F, Coquard IR, de La Motte Rouge T.
  • Réseaux : Réseaux: non classé
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Planning With Patient-Specific Rectal Sub-Region Constraints Decreases Probability of Toxicity in Prostate Cancer Radiotherapy.

Background: A rectal sub-region (SRR) has been previously identified by voxel-wise analysis in the inferior-anterior part of the rectum as highly predictive of rectal bleeding (RB) in prostate cancer radiotherapy.

  • Ref: Front Oncol. 2020 Sep 11;10:1597.
  • Année de publication : 2020
  • Auteurs : Lafond C, Barateau A, N'Guessan J, Perichon N, Delaby N, Simon A, Haigron P, Mylona E, Acosta O, de Crevoisier R.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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PTPN11 mutations in canine and human disseminated histiocytic sarcoma.

In humans, histiocytic sarcoma (HS) is an aggressive cancer involving histiocytes. Its rarity and heterogeneity explain that treatment remains a challenge.

  • Ref: Int J Cancer. 2020 Sep 15;147(6):1657-1665.
  • Année de publication : 2020
  • Auteurs : Hédan B, Rault M, Abadie J, Ulvé R, Botherel N, Devauchelle P, Copie-Bergman C, Cadieu E, Parrens M, Alten J, Zalcman EL, Cario G, Damaj G, Mokhtari K, Le Loarer F, Coulomb-Lhermine A, Derrien T, Hitte C, Bachelot L, Breen M, Gilot D, Blay JY, Donadieu J, André C.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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Phase II Study of Pembrolizumab As First-Line, Single-Drug Therapy for Patients With Unresectable Cutaneous Squamous Cell…

Purpose: To evaluate first-line pembrolizumab monotherapy efficacy and safety in patients with unresectable cutaneous squamous cell carcinomas (CSCCs).

  • Ref: J Clin Oncol. 2020 Sep 10;38(26):3051-3061.
  • Année de publication : 2020
  • Auteurs : Maubec E, Boubaya M, Petrow P, Beylot-Barry M, Basset-Seguin N, Deschamps L, Grob JJ, Dréno B, Scheer- Senyarich I, Bloch-Queyrat C, Leccia MT, Stefan A, Saiag P, Grange F, Meyer N, de Quatrebarbes J, Dinulescu M, Legoupil D, Machet L, Dereure O, Zehou O, Montaudié H, Wierzbicka-Hainaut E, Le Corre Y, Mansard S, Guégan S, Arnault JP, Dalac S, Aubin F, Alloux C, Lopez I, Cherbal S, Tibi A, Lévy V.
  • Réseaux : Réseaux: non classé
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