Les publications

Page en cours de mise à jour... Retrouvez ici les publications des équipes de recherche du CGO

Réseaux Appels à projets Actualités
384 publications
Année de publication :
Réseaux :

LINGO family receptors are differentially expressed in the mouse brain and form native multimeric complexes.

Leucine-rich repeat and immunoglobin-domain containing (LRRIG) proteins that are commonly involved in protein-protein interactions play important roles in nervous system development and maintenance. LINGO-1, one of this family members, is characterized as a negative regulator of neuronal survival, axonal regeneration, and oligodendrocyte precursor cell (OPC) differentiation into mature myelinating oligodendrocytes.

  • Ref: DOI : 10.1096/fj.202000826R
  • Année de publication : 2020
  • Auteurs : Guillemain A, Laouarem Y, Cobret L, Štefok D, Chen W, Bloch S, Zahaf A, Blot L, Reverchon F, Normand T, Decoville M, Grillon C, Traiffort E, Morisset-Lopez S.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
Lire la publication

Biopsy Grade Group as a reliable prognostic factor for BCR in Afro-Caribbean men with intermediate- and…

The Grade Group (GG) classification is recommended by guidelines as a reliable prognostic factor of prostate cancer. However, most studies have been performed on the Caucasian population.

  • Ref: doi: 10.1007/s00345-019-02931-3
  • Année de publication : 2020
  • Auteurs : Perrot E, Seddik S, Gourtaud G, Eyraud R, Roux V, Moureaux C, Blanchet P, Brureau L
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
Lire la publication

Active surveillance in prostate cancer is possible for Afro-Caribbean population: Comparison of oncological outcomes with a…

Prostate cancer is supposedly more aggressive among Afro-Caribbean men. There is a lack of data in this population for active surveillance. Published series are retrospective or have small samples and results are discordant.

  • Ref: doi: 10.1016/j.purol.2020.05.006
  • Année de publication : 2020
  • Auteurs : Percot M, Robert G, Bladou F, Ferrière JM, Bensadoun H, Bernhard JC, Alezra E, Capon G, Sénéchal C, Gourtaud G, Brureau L, Roux V, Blanchet P, Eyraud R
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
Lire la publication

COVID-19 and people followed for breast cancer: French guidelines for clinical practice of Nice-St Paul de…

  • Ref: doi: 10.1016/j.bulcan.2020.03.008
  • Année de publication : 2020
  • Auteurs : Gligorov J, Bachelot T, Pierga JY, Antoine EC, Balleyguier C, Barranger E, Belkacemi Y, Bonnefoi H, Bidard FC, Ceugnart L, Classe JM, Cottu P, Coutant C, Cutuli B, Dalenc F, Darai E, Dieras V, Dohollou N, Giacchetti S, Goncalves A, Hardy-Bessard AC, Houvenaeghel G, Jacquin JP, Jacot W, Levy C, Mathelin C, Nisand I, Petit T, Petit T, Poncelet E, Rivera S, Rouzier R, Salmon R, Scotté F, Spano JP, Uzan C, Zelek L, Spielmann M, Penault-Llorca F, Namer M, Delaloge S
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
Lire la publication

Involvement of the M-CSF/IL-34/CSF-1R pathway in malignant pleural mesothelioma.

Malignant pleural mesothelioma (MPM) is a rare and aggressive cancer related to asbestos exposure. The tumor microenvironment content, particularly the presence of macrophages, was described as crucial for the development of the disease.

  • Ref: doi: 10.1136/jitc-2019-000182
  • Année de publication : 2020
  • Auteurs : Blondy T, d'Almeida SM, Briolay T, Tabiasco J, Meiller C, Chéné AL, Cellerin L, Deshayes S, Delneste Y, Fonteneau JF, Boisgerault N, Bennouna J, Grégoire M, Jean D, Blanquart C
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

Contribution of the SYK Tyrosine kinase expression to human iNKT self-reactivity.

Invariant Natural Killer T (iNKT) cells are particular T lymphocytes at the frontier between innate and adaptative immunities. They participate in the elimination of pathogens or tumor cells, but also in the development of allergic reactions and autoimmune diseases. From their first descriptions, the phenomenon of self-reactivity has been described.

  • Ref: doi: 10.1002/eji.201948416
  • Année de publication : 2020
  • Auteurs : Perroteau J, Navet B, Devilder MC, Hesnard L, Scotet E, Gapin L, Saulquin X, Gautreau-Rolland L
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

Anti-Glucosylsphingosine Autoimmunity, JAK2V617F-Dependent Interleukin-1β and JAK2V617F-Independent Cytokines in Myeloproliferative Neoplasms.

Inflammatory cytokines play a major role in myeloproliferative neoplasms (MPNs) as regulators of the MPN clone and as mediators of clinical symptoms and complications. Firstly, we investigated the effect of JAK2V617F on 42 molecules linked to inflammation.

  • Ref: doi: 10.3390/cancers12092446
  • Année de publication : 2020
  • Auteurs : Allain-Maillet S, Bosseboeuf A, Mennesson N, Bostoën M, Dufeu L, Choi EH, Cleyrat C, Mansier O, Lippert E, Le Bris Y, Gombert JM, Girodon F, Pettazzoni M, Bigot-Corbel E, Hermouet S
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

Analysis of the Targets and Glycosylation of Monoclonal IgAs From MGUS and Myeloma Patients.

Previous studies showed that monoclonal immunoglobulins G (IgGs) of “monoclonal gammopathy of undetermined significance” (MGUS) and myeloma were hyposialylated, thus presumably pro-inflammatory, and for about half of patients, the target of the monoclonal IgG was either a virus-Epstein…

  • Ref: doi: 10.3389/fimmu.2020.00854
  • Année de publication : 2020
  • Auteurs : Bosseboeuf A, Seillier C, Mennesson N, Allain-Maillet S, Fourny M, Tallet A, Piver E, Lehours P, Mégraud F, Berthelot L, Harb J, Bigot-Corbel E, Hermouet S
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

Characteristics of MGUS and Multiple Myeloma According to the Target of Monoclonal Immunoglobulins, Glucosylsphingosine, or Epstein-Barr…

: Chronic stimulation by infectious or self-antigens initiates subsets of monoclonal gammopathies of undetermined significance (MGUS), smoldering multiple myeloma (SMM), or multiple myeloma (MM). Recently, glucosylsphingosine (GlcSph) was reported to be the target of one third of monoclonal immunoglobulins (Igs).

  • Ref: doi: 10.3390/cancers12051254
  • Année de publication : 2020
  • Auteurs : Bosseboeuf A, Mennesson N, Allain-Maillet S, Tallet A, Piver E, Decaux O, Moreau C, Moreau P, Lehours P, Mégraud F, Salle V, Bigot-Corbel E, Harb J, Hermouet S
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication