Les publications

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393 publications
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Phase II Study of Pembrolizumab As First-Line, Single-Drug Therapy for Patients With Unresectable Cutaneous Squamous Cell…

Purpose: To evaluate first-line pembrolizumab monotherapy efficacy and safety in patients with unresectable cutaneous squamous cell carcinomas (CSCCs).

  • Ref: J Clin Oncol. 2020 Sep 10;38(26):3051-3061.
  • Année de publication : 2020
  • Auteurs : Maubec E, Boubaya M, Petrow P, Beylot-Barry M, Basset-Seguin N, Deschamps L, Grob JJ, Dréno B, Scheer- Senyarich I, Bloch-Queyrat C, Leccia MT, Stefan A, Saiag P, Grange F, Meyer N, de Quatrebarbes J, Dinulescu M, Legoupil D, Machet L, Dereure O, Zehou O, Montaudié H, Wierzbicka-Hainaut E, Le Corre Y, Mansard S, Guégan S, Arnault JP, Dalac S, Aubin F, Alloux C, Lopez I, Cherbal S, Tibi A, Lévy V.
  • Réseaux : Réseaux: non classé
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Overall survival among chemotherapy-naïve castration-resistant prostate cancer patients under abiraterone versus enzalutamide.

Abiraterone acetate (ABI) and enzalutamide (ENZ) are considered to be clinically relevant comparators among chemotherapy-naive patients with castration-resistant prostate cancer.

  • Ref: Am J Epidemiol. 2020 Sep 18:kwaa190.
  • Année de publication : 2020
  • Auteurs : Scailteux LM, Campillo-Gimenez B, Kerbrat S, Despas F, Mathieu R, Vincendeau S, Balusson F, Happe A, Nowak E, Oger E.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Neurofibromin Structure, Functions and Regulation.

Neurofibromin is a large and multifunctional protein encoded by the tumor suppressor gene NF1, mutations of which cause the tumor predisposition syndrome neurofibromatosis type 1 (NF1).

  • Ref: Cells. 2020 Oct 27;9(11):E2365.
  • Année de publication : 2020
  • Auteurs : Bergoug M, Doudeau M, Godin F, Mosrin C, Vallée B, Bénédetti H.
  • Réseaux : Réseaux: « Molécules Marines, Métabolisme et Cancer »
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African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer.

Polygenic hazard score (PHS) models are associated with age at diagnosis of prostate cancer. Our model developed in Europeans (PHS46) showed reduced performance in men with African genetic ancestry.

  • Ref: Int J Cancer. 2020 Sep 15.
  • Année de publication : 2020
  • Auteurs : Karunamuni RA, Huynh-Le MP, Fan CC, Thompson W, Eeles RA, Kote-Jarai Z, Muir K; UKGPCS Collaborators, Lophatananon A, Tangen CM, Goodman PJ, Thompson IM Jr, Blot WJ, Zheng W, Kibel AS, Drake BF, Cussenot O, Cancel-Tassin G, Menegaux F, Truong T, Park JY, Lin HY, Bensen JT, Fontham ETH, Mohler JL, Taylor JA, Multigner L, Blanchet P, Brureau L, Romana M, Leach RJ, John EM, Fowke J, Bush WS, Aldrich M, Crawford DC, Srivastava S, Cullen JC, Petrovics G, Parent MÉ, Hu JJ, Sanderson M, Mills IG, Andreassen OA, Dale AM, Seibert TM; PRACTICAL Consortium.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Targeted-Alpha-Therapy Combining Astatine-211 and anti-CD138 Antibody in A Preclinical Syngeneic Mouse Model of Multiple Myeloma Minimal…

Despite therapeutic progress in recent years with the introduction of targeted therapies (daratumumab, elotuzumab), multiple myeloma remains an incurable cancer.

  • Ref: Cancers (Basel). 2020 Sep 22;12(9):2721.
  • Année de publication : 2020
  • Auteurs : Gouard S, Maurel C, Marionneau-Lambot S, Dansette D, Bailly C, Guérard F, Chouin N, Haddad F, Alliot C, Gaschet J, Eychenne R, Kraeber-Bodéré F, Chérel M.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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68Ga-Labelled Carbon Nanoparticles for Ventilation PET/CT Imaging: Physical Properties Study and Comparison with Technegas®.

The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr4+ by considering polynuclear species.

  • Ref: Mol Imaging Biol. 2020 Sep 4.
  • Année de publication : 2020
  • Auteurs : Blanc-Béguin F, Eliès P, Robin P, Tripier R, Kervarec N, Lemarié CA, Hennebicq S, Tromeur C, Cogulet V, Salaün PY, Le Roux PY.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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From a PMT-based to a SiPM-based PET system: a study to define matched acquisition/reconstruction parameters and…

Background: The purpose of this work was to propose an approach based on noise measurement to adapt present clinical acquisition and reconstruction parameters adapted to a PMT-based system (Biograph mCT) to a SiPM-based system (Biograph Vision 450) sharing identical geometrical properties.

  • Ref: EJNMMI Phys. 2020 Sep 3;7(1):55.
  • Année de publication : 2020
  • Auteurs : Carlier T, Ferrer L, Conti M, Bodet-Milin C, Rousseau C, Bercier Y, Bendriem B, Kraeber-Bodéré F.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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Enabling Indium Channels for Mass Cytometry by Using Reinforced Cyclam-Based Chelating Polylysine.

The synthesis of a polylysine polymer functionalized with the previously reported astonishingly inert [In(cb-te2pa)]+ chelate was performed.

  • Ref: Bioconjug Chem. 2020 Sep 16;31(9):2103-2115.
  • Année de publication : 2020
  • Auteurs : Grenier L, Beyler M, Closson T, Zabinyakov N, Bouzekri A, Zhang Y, Pichaandi JM, Winnik MA, Liu P, Ornatsky OI, Baranov V, Tripier R.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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Reply to the ‘Comment on “Investigation of Zr(iv) and 89Zr(iv) complexation with hydroxamates: progress towards designing…

The alternative analysis of A. Bianchi and M. Savastano is a valuable contribution to the understanding of the complex systems at stake in the complexation chemistry of Zr4+ by considering polynuclear species.

  • Ref: Chem Commun (Camb). 2020 Oct 25;56(83):12667-12668.
  • Année de publication : 2020
  • Auteurs : Guérard F, Lee YS, Tripier R, Szajek LP, Deschamps JR, Brechbiel MW.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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Questioning the Affinity of Electrophilic Astatine for Sulfur-containing Compounds: Unexpected Bindings Revealed.

The affinity of AtO+ for around 20 model ligands (L), carrying functionalized oxygen, sulfur, and nitrogen atoms, has been assessed through a combined experimental and theoretical methodology.

  • Ref: Inorg Chem. 2020 Oct 5;59(19):13923-13932.
  • Année de publication : 2020
  • Auteurs : Bassal F, Champion J, Pardoue S, Seydou M, Sabatié-Gogova A, Deniaud D, Questel JL, Montavon G, Galland N.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
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