Les publications

Page en cours de mise à jour... Retrouvez ici les publications des équipes de recherche du CGO

Réseaux Appels à projets Actualités
407 publications
Année de publication :
Réseaux :

Human Lymphoid Stromal Cells Contribute to Polarization of Follicular T Cells Into IL-4 Secreting Cells.

Fibroblastic reticular cells (FRCs) are the specialized lymphoid stromal cells initially identified as triggering T-cell recruitment and dynamic motion in secondary lymphoid organs. Interestingly, FRCs also display antigen presentation capacities and support lymphocyte survival. CXCR5+CD4+ follicular T cells are important players of B-cell maturation and antibody response.

  • Ref: Front Immunol. 2020 Oct 2;11:559866.
  • Année de publication : 2020
  • Auteurs : Misiak J, Jean R, Rodriguez S, Deleurme L, Lamy T, Tarte K, Amé-Thomas P.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
Lire la publication

Three-Dimensional Culture Systems in Gastric Cancer Research.

Gastric cancer (GC), which includes cancer of the esophagus, the oesophagogastric junction, and the stomach fundus, is highly deadly with strong regional influence, Asia being the most affected.

  • Ref: Cancers (Basel). 2020 Sep 29;12(10):2800.
  • Année de publication : 2020
  • Auteurs : Alzeeb G, Metges JP, Corcos L, Le Jossic-Corcos C.
  • Réseaux : Réseaux: « Niches et Epigénétique des Tumeurs »
Lire la publication

Antibody-Drug Conjugates: The Last Decade.

An armed antibody (antibody-drug conjugate or ADC) is a vectorized chemotherapy, which results from the grafting of a cytotoxic agent onto a monoclonal antibody via a judiciously constructed spacer arm. ADCs have made considerable progress in 10 years.

  • Ref: Pharmaceuticals (Basel). 2020 Sep 14;13(9):245.
  • Année de publication : 2020
  • Auteurs : Joubert N, Beck A, Dumontet C, Denevault-Sabourin C.
  • Réseaux : Réseaux: « Vectorisation, Imagerie, Radiothérapies »
Lire la publication

Leukemic evolution of polycythemia vera and essential thrombocythemia: genomic profiles predict time to transformation.

Among myeloproliferative neoplasms, polycythemia vera (PV) and essential thrombocythemia (ET) are the 2 entities associated with the most chronic disease course. Leukemic evolution occurs rarely but has a grim prognosis.

  • Ref: Blood Adv. 2020 Oct 13;4(19):4887-4897.
  • Année de publication : 2020
  • Auteurs : Luque Paz D, Jouanneau-Courville R, Riou J, Ianotto JC, Boyer F, Chauveau A, Renard M, Chomel JC, Cayssials E, Gallego-Hernanz MP, Pastoret C, Murati A, Courtier F, Rousselet MC, Quintin-Roué I, Cottin L, Orvain C, Thépot S, Chrétien JM, Delneste Y, Ifrah N, Blanchet O, Hunault-Berger M, Lippert E, Ugo V.
  • Réseaux : Réseaux: « Immunothérapies »
Lire la publication

A Germline Variant at 8q24 Contributes to Familial Clustering of Prostate Cancer in Men of African…

Although men of African ancestry have a high risk of prostate cancer (PCa), no genes or mutations have been identified that contribute to familial clustering of PCa in this population.

  • Ref: Eur Urol. 2020 Sep;78(3):316-320.
  • Année de publication : 2020
  • Auteurs : Darst BF, Wan P, Sheng X, Bensen JT, Ingles SA, Rybicki BA, Nemesure B, John EM, Fowke JH, Stevens VL, Berndt SI, Huff CD, Strom SS, Park JY, Zheng W, Ostrander EA, Walsh PC, Srivastava S, Carpten J, Sellers TA, Yamoah K, Murphy AB, Sanderson M, Crawford DC, Gapstur SM, Aldrich MC, Cussenot O, Yeager M, Petrovics G, Cullen J, Neslund-Dudas C, Kittles RA, Xu J, Stern MC, Kote-Jarai Z, Govindasami K, Chokkalingam AP, Multigner L, Parent ME, Menegaux F, Cancel-Tassin G, Kibel AS, Klein EA, Goodman PJ, Drake BF, Hu JJ, Clark PE, Blanchet P, Casey G, Hennis AJM, Lubwama A, Thompson IM Jr, Leach R, Gundell SM, Pooler L, Xia L, Mohler JL, Fontham ETH, Smith GJ, Taylor JA, Eeles RA, Brureau L, Chanock SJ, Watya S, Stanford JL, Mandal D, Isaacs WB, Cooney K, Blot WJ, Conti DV, Haiman CA.
  • Réseaux : Réseaux: non classé
Lire la publication

Stratifying patients with intermediate-risk prostate cancer.

Objective: Intermediate-risk prostate cancer regroups heterogeneous patients with different oncologic outcomes. Aim of the study is to validate a novel intermediate-risk subclassification (“magnetic resonance imaging [MRI] subclassification”) that defines favorable and unfavorable diseases based on multiparametric MRI parameters and compare it to NCCN and AUA intermediate-risk subclassifications.

  • Ref: Urol Oncol. 2020 Oct 8:S1078-1439(20)30399-9.
  • Année de publication : 2020
  • Auteurs : Diamand R, Ploussard G, Roumiguié M, Malavaud B, Oderda M, Gontero P, Fourcade A, Fournier G, Benamran D, Iselin C, Fiard G, Descotes JL, Peltier A, Simone G, Roche JB, Roumeguère T, Albisinni S.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
Lire la publication

Neurofibromin Structure, Functions and Regulation.

Neurofibromin is a large and multifunctional protein encoded by the tumor suppressor gene NF1, mutations of which cause the tumor predisposition syndrome neurofibromatosis type 1 (NF1).

  • Ref: Cells. 2020 Oct 27;9(11):E2365.
  • Année de publication : 2020
  • Auteurs : Bergoug M, Doudeau M, Godin F, Mosrin C, Vallée B, Bénédetti H.
  • Réseaux : Réseaux: « Molécules Marines, Métabolisme et Cancer »
Lire la publication

Overall survival among chemotherapy-naïve castration-resistant prostate cancer patients under abiraterone versus enzalutamide.

Abiraterone acetate (ABI) and enzalutamide (ENZ) are considered to be clinically relevant comparators among chemotherapy-naive patients with castration-resistant prostate cancer.

  • Ref: Am J Epidemiol. 2020 Sep 18:kwaa190.
  • Année de publication : 2020
  • Auteurs : Scailteux LM, Campillo-Gimenez B, Kerbrat S, Despas F, Mathieu R, Vincendeau S, Balusson F, Happe A, Nowak E, Oger E.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
Lire la publication