Les publications

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398 publications
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Pimasertib Versus Dacarbazine in Patients With Unresectable NRAS-Mutated Cutaneous Melanoma: Phase II, Randomized, Controlled Trial with…

This study investigated the efficacy and safety of pimasertib (MEK1/MEK2 inhibitor) versus dacarbazine (DTIC) in patients with untreated NRAS-mutated melanoma.

  • Ref: doi: 10.3390/ijms21145025
  • Année de publication : 2020
  • Auteurs : Lebbé C, Dutriaux C, Lesimple T, Kruit W, Kerger J, Thomas L, Guillot B, Braud F, Garbe C, Grob JJ, Loquai C, Ferraresi V, Robert C, Vasey P, Conry R, Isaacs R, Espinosa E, Schueler A, Massimini G, Dréno B
  • Réseaux : Réseaux: « Immunothérapies »
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Quantitative chimerism in CD3-negative mononuclear cells predicts prognosis in acute myeloid leukemia patients after hematopoietic stem…

Relapse is a major complication of acute myeloid leukemia (AML) after allogeneic hematopoietic stem cell transplantation (SCT). The objective of our study was to evaluate chimerism monitoring on the CD3-negative mononuclear cells by RQ-PCR to predict relapse of patients allografted for AML and to compare its performance with WT1 quantification.

  • Ref: doi: 10.3390/cancers12071727
  • Année de publication : 2020
  • Auteurs : Bouvier A, Riou J, Thépot S, Sutra Del Galy A, François S, Schmidt A, Orvain C, Estienne MH, Villate A, Luque Paz D, Cottin L, Ribourtout B, Beucher A, Delneste Y, Ifrah N, Ugo V, Hunault-Berger M, Blanchet O
  • Réseaux : Réseaux: « Immunothérapies »
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Impact of initial treatment and prognostic factors on postprogression survival in BRAF-mutated metastatic melanoma treated with…

We sought to identify patient subgroups with distinct postprogression overall survival (ppOS) outcomes and investigate the impact of original treatment assignment and initial postprogression treatment (ppRx) on ppOS.

  • Ref: doi: 10.1186/s12967-020-02458-x
  • Année de publication : 2020
  • Auteurs : Ascierto PA, Ribas A, Larkin J, McArthur GA, Lewis KD, Hauschild A, Flaherty KT, McKenna E, Zhu Q, Mun Y, Dréno B
  • Réseaux : Réseaux: « Immunothérapies »
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[Editorial].

  • Ref: doi: 10.1016/j.purol.2020.06.009
  • Année de publication : 2020
  • Auteurs : Mathieu R.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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External Validation of the 2019 Briganti Nomogram for the Identification of Prostate Cancer Patients Who Should…

The 2019 Briganti nomogram was developed to calculate the risk of lymph node invasion (LNI) and identify prostate cancer (PCa) patients diagnosed with magnetic resonance imaging (MRI)-targeted biopsy who should be considered for an extended pelvic lymph node dissection (ePLND)

  • Ref: doi: 10.1016/j.eururo.2020.03.023
  • Année de publication : 2020
  • Auteurs : Gandaglia G, Martini A, Ploussard G, Fossati N, Stabile A, De Visschere P, Borgmann H, Heidegger I, Steinkohl F, Kretschmer A, Marra G, Mathieu R, Surcel C, Tilki D, Tsaur I, Valerio M, Van den Bergh R, Ost P, Gontero P, Montorsi F, Briganti A
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Radical prostatectomy for prostate cancer, perioperative management by French urologists in 2018.

Prostatectomy (PT) is a common procedure performed by many urologists. In 2018, 20,207 prostatectomies were performed in France, and few studies evaluated the perioperative habits of urologists.

  • Ref: doi: 10.1016/j.purol.2020.06.007
  • Année de publication : 2020
  • Auteurs : Gas J, Dominique I, Mathieu R, Poinas G, Cuvelier G, Rebillard X, Corbel L
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Exercise shapes redox signaling in cancer.

In this paper of the special issue dedicated for the Olympics 2020, we put the light on an exciting facet of exercise-oncology, which may still be unknown to some audience. Accumulating convincing evidences show that exercise reduces cancer progression and recurrence mainly in colon and breast cancer patients.

  • Ref: doi: 10.1016/j.redox.2020.101439
  • Année de publication : 2020
  • Auteurs : Assi M, Dufresne S, Rébillard A
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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Specificities of small cell neuroendocrine prostate cancer: Adverse prognostic value of TTF1 expression.

To determine whether small cell neuroendocrine prostate cancers (NEPCa) emerging after anti-androgen treatments are different from the rarest cases diagnosed de novo, and to identify effective predictive markers.

  • Ref: doi: 10.1016/j.urolonc.2020.07.007
  • Année de publication : 2020
  • Auteurs : Cancel M, Castellier C, Debiais-Delpech C, et al.
  • Réseaux : Réseaux: « Cancers des Tissus Hormono-dépendants »
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